Background: Contemporary psychiatry faces a double challenge: the global burden of depression, anxiety, loneliness, trauma-related distress and functional impairment continues to grow, while many people remain unable or unwilling to access conventional mental health services. Preventive, community-based and recoveryoriented approaches are therefore needed as complements—not substitutes—to diagnosis, psychotherapy and pharmacological care. Objective: This article proposes the Pain-to-Vitamin Art-Based Mental Health Framework (PV-ART), a structured, meaning-centered and arts-informed model designed to transform emotional pain into psychological nutrients through expression, narrative reorganization, social connection and habit formation. Methods: A conceptual and translational review was conducted by integrating evidence from psychiatry, psychology, behavioral science, salutogenesis, resilience research, arts-and-health literature, music therapy, visual art therapy, behavioral activation and validated mental health measurement. Results: PV-ART is organized around four sequential clinical-educational movements: Naming pain, expressing pain through symbolic creation, converting pain into meaning and consolidating change through micro-habits. The model is intended for adults with mild to moderate psychological distress, subclinical symptoms, recovery needs or relapse-prevention goals, and should be delivered under appropriate ethical and clinical safeguards. The article presents an eight-session protocol, outcome measures, implementation criteria, risk management procedures and research recommendations for pilot feasibility studies and randomized controlled trials. Conclusions: Art-based and meaning-centered interventions may offer a promising adjunctive route to enhance emotional literacy, agency, social belonging and recoveryoriented well-being. PV-ART requires empirical validation but provides a clinically cautious, culturally adaptable and measurable framework for preventive psychiatry and mental health promotion.